The 46 Home Run Club Player Home Runs Year Barry Bonds 73 2001 Mark McGwire 70 1998 Sammy Sosa 66 1998 Mark McGwire 65 1999 Sammy Sosa 64 2001 Sammy Sosa 63 1999 Roger Maris 61 1961 Babe Ruth 60 1927 Babe Ruth 59 1921 Jimmie Foxx 58 1932 Hank Greenberg 58 1938 Ryan Howard 58 2006 Mark McGwire 58 1997 Luis Gonzalez 57 2001 Alex Rodriguez 57 2002 Ken Griffey 56 1997 Ken Griffey 56 1998 Hack Wilson 56 1930 Jose Bautista 54 2010 Ralph Kiner 54 1949 Mickey Mantle 54 1961 David Ortiz 54 2006 Alex Rodriguez 54 2007 Babe Ruth 54 1920 Babe Ruth 54 1928 George Foster 52 1977 Mickey Mantle 52 1956 Willie Mays 52 1965 Mark McGwire 52 1996 Alex Rodriguez 52 2001 Jim Thome 52 2002 Cecil Fielder 51 1990 Andruw Jones 51 2005 Ralph Kiner 51 1947 Willie Mays 51 1955 Johnny Mize 51 1947 Brady Anderson 50 1996 Albert Belle 50 1995 Prince Fielder 50 2007 Jimmie Foxx 50 1938 Sammy Sosa 50 2000 Greg Vaughn 50 1998 Albert Belle 49 1998 Barry Bonds 49 2000 Andre Dawson 49 1987 Lou Gehrig 49 1934 Lou Gehrig 49 1936 Shawn Green 49 2001 Ken Griffey 49 1996 Todd Helton 49 2001 Harmon Killebrew 49 1964 Harmon Killebrew 49 1969 Ted Kluszewski 49 1954 Willie Mays 49 1962 Mark McGwire 49 1987 Albert Pujols 49 2006 Frank Robinson 49 1966 Babe Ruth 49 1930 Sammy Sosa 49 2002 Jim Thome 49 2001 Larry Walker 49 1997 Albert Belle 48 1996 Adrian Beltre 48 2004 Jimmie Foxx 48 1933 Ken Griffey 48 1999 Frank Howard 48 1969 Ryan Howard 48 2008 Harmon Killebrew 48 1962 Dave Kingman 48 1979 Alex Rodriguez 48 2005 Mike Schmidt 48 1980 Willie Stargell 48 1971 Hank Aaron 47 1971 Jeff Bagwell 47 2000 Ernie Banks 47 1958 George Bell 47 1987 Andres Galarraga 47 1996 Lou Gehrig 47 1927 Troy Glaus 47 2000 Juan Gonzalez 47 1996 Ryan Howard 47 2007 Reggie Jackson 47 1969 Ralph Kiner 47 1950 Ted Kluszewski 47 1955 Eddie Mathews 47 1953 Willie Mays 47 1964 Kevin Mitchell 47 1989 David Ortiz 47 2005 Rafael Palmeiro 47 1999 Rafael Palmeiro 47 2001 Albert Pujols 47 2009 Alex Rodriguez 47 2003 Babe Ruth 47 1926 Jim Thome 47 2003 Barry Bonds 46 1993 Barry Bonds 46 2002 Jose Canseco 46 1998 Vinny Castilla 46 1998 Orlando Cepeda 46 1961 Joe DiMaggio 46 1937 Adam Dunn 46 2004 Prince Fielder 46 2009 Lou Gehrig 46 1931 Jim Gentile 46 1961 Juan Gonzalez 46 1993 Harmon Killebrew 46 1961 Derrek Lee 46 2005 Eddie Mathews 46 1959 Carlos Pena 46 2007 Albert Pujols 46 2004 Jim Rice 46 1978 Babe Ruth 46 1924 Babe Ruth 46 1929 Babe Ruth 46 1931 Alfonso Soriano 46 2006